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What is FMT?

FMT is the infusion of a healthy microbiome in the form of donor faecal material. The microbiome from the carefully screened donor is prepared into treatments that may be delivered via colonoscopy, orogastric tube, or enema. the transplant then repopulates the recipients gut bacteria with the healthy colonic microflora of the donor.
The effectiveness of FMT has been established in clinical trials for the treatment of recurrent Clostridium difficile, and there are several studies including a benefit for colitis, inflammatory bowel disease, irritable bowel syndrome, idiopathic constipation and a variety of non-digestive diseases.

Why Does it Help?

A plethora of recent studies have indicated that our gut bacteria play an integral role not only in our digestive and immune system funtion, but also in many other unexpected aspects of physical and mental health. More discoveries are being revealed evry day, and the common theme is that an imbalance in our microbiome can predispose to disease development.

Re-establishment of a diversity of bacteria in the colon of the patient is the proposed mechanism by which FMT results in clinical improvement in patients with C. diff and other diseases.

What are the Risks?

FMT is not a new therapy. There is evidence in Chinese medical literature from the fourth century describing a procedure that required ingestion of human faecal matter to treat abdominal diseases.

In Western medicine the treatment has been used since the 1950s. In very rare cases resulted in the transmission of disease from the donor to the recipient. Effective screening of donor material and treatment processing under strict conditions is the most effective way to minimise the risk of disease transmission.

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