Donors Selection & Screening



How Our Donors Are Screened

Our screening program is based on the Current Consensus Guidance on Donor Screening and Stool Testing for FMT that were written in July 2013 by Infectious Diseases Society of America (IDSA), American Society of Gastroenterology (ASGE), North American Society of Paediatric Gastroenterology, Hepatology & Nutrition (NASPGHAN), American Gastroenterological Association (AGA), American College of Gastroenterology (ACG).


Donor Selection Criteria

Preferred donors:

  • well-screened intimate, long-time partner of adult patient
  • well-screened relative
  • well-screened close family friend
  • well-screened non-related universal donor
  • children could also potentially serve as donors as long as both parental consent and child assent (i.e., agreement to serve as a donor) are obtained

Donor exclusion criteria:

  • A history of antibiotic treatment during the preceding 3 months of donation
  • A history of intrinsic gastrointestinal illnesses, including inflammatory bowel disease, irritable bowel syndrome, gastrointestinal malignancies or major gastrointestinal surgical procedures
  • A history of autoimmune disease or atopic illnesses or ongoing immune modulating therapy
  • A history of chronic pain syndromes (fibromyalgia, chronic fatigue) or neurologic, neurodevelopmental disorders
  • Metabolic syndrome, obesity (BMI of >30), or moderate-to-severe undernutrition (malnutrition)
  • A history of malignant illnesses or ongoing oncologic therapy
  • A history of any mental illness, anxiety, depression, scizophrenia, personality disorder, eating disorder, bulimia, anorexia nervosa


Donor Screening

Donor medical history questionnaires are filled out by all donors and screened by our doctors and our clinic nurse prior to medical examination. This is designed to screen all potential donors for any illnesses or health problems that would preclude FMT donation. It is similar to current protocols for screening blood donors and is comprehensive.

Selected donors must have a regular healthy bowel habit and avoid foods at risk of contamination and commence the high fibre diet to maintain and enrich their gut bacteria.


Blood Testing

HAV-IgM, HBsAg, anti-HCV-Ab, HIV-EIA, RPR, FBE, EBV, CMV, Toxoplasma, HLAB27, ANA, Coeliac serology, B12, Folate, Urea & Creatinine, Electrolytes, Thyroid function, Rheumatoid factor, CRP - (annually)


Stool Testing

  • MCS faeces for enteric viruses, pathogenic bacteria and parasite cysts and ova (monthly)
  • Stool culture for c.diff and cdiff toxin B (monthly)
  • Stool PCR for enteric pathogens and parasites (monthly)
  • Complete faecal bioscreen to assess comprehensive make up of gut microbiota (annually)